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Emerging role of thiamine therapy for prevention and treatment of early stage diabetic nephropathy

By admin - Posted on 17 March 2011

Rabbani N, Thornalley PJ. Emerging role of thiamine therapy for prevention and treatment of early stage diabetic nephropathy. Diabetes Obes Metab. 2011 Feb 22. doi: 10.1111/j.1463-1326.2011.01384.x. [Epub ahead of print] PubMed PMID: 21342411

Thiamine supplementation prevented the development of early-stage nephropathy in diabetic rats and reversed increased urinary albumin excretion in patients with type 2 diabetes and microalbuminuria in two recent clinical trials.

http://www.ncbi.nlm.nih.gov/pubmed/21342411

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Access to Parenteral Thiamine

Biological Therapies supplies a range of registered injections containing parenteral thiamine.
See the TGA website: http://www.tga.gov.au/safety/alerts-medicine-ivthiamine-100728.htm
See also the SHPA website: SHPA Manufacturers Alerts (Thiamine Injection)

Pub Med Highlights

Delayed treatment with vitamin C and N-acetyl-L cysteine protects Schwann cells without compromising the anti-myeloma activity of bortezomib

Effect of oral suplementation of vitamin C on intestinal anastomotic resistance

Assessing the survival of mrc-5 and a549 cell lines upon exposure to ascorbic Acid and sodium ascorbate - biomed 2011

Protective effects of vitamin C against haematological and biochemical toxicity induced by deltamethrin in male Wistar rats

Vitamin C status is related to proinflammatory responses and impaired vascular endothelial function in healthy, college-aged lean and obese men

Does prophylactic therapy with antioxidant vitamins have an effect on atrial fibrillation following cardiac surgery?

Dietary Intakes of Antioxidant Vitamins and Mortality From Cardiovascular Disease - The JACC Study

Transmission of hepatitis C virus to recipients of parenteral vitamin therapy in a primary care facility.

Ascorbate decreases the mucosal immune inflammatory response to gliadin in coeliac disease patient

Vitamin C increases the apoptosis via up-regulation p53 during cisplatin treatment in human colon cancer cells

Intravenous ascorbic acid (vitamin C) administration in myomectomy, a prospective, randomized, clinical trial

Preclinical evaluation of the antitumor activity of bortezomib in combination with vitamin C

Emerging role of thiamine therapy for prevention and treatment of early stage diabetic nephropathy

Revisiting the ALA-N (alpha-lipoic acid - low-dose naltrexone) protocol for people with pancreatic cancer

Effect of thiamine administration on metabolic profile, cytokines and inflammatory markers in type 2 diabetes patients

Meet the team

From Ian's Desk

Inaugural Meeting of World Federation of Chinese Medicine Societies - WFCMS - China May 2011 - Conference and Invitation

Intravenous ascorbic acid to prevent and treat cancer-associated sepsis?

Attending Japanese College of Intravenous Therapy 2010 - a great success

Homocysteine-Lowering by B Vitamins Slows the Rate of Accelerated Brain Atrophy in Mild Cognitive Impairment: RCT

Pharmacological ascorbic acid suppresses syngeneic tumor growth and metastases in hormone-refractory prostate cancer

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